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Ulcerative Colitis

Ulcerative Colitis

Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) characterized by inflammation and ulcers in the lining of the colon and rectum. It is a type of autoimmune disorder in which the body’s immune system mistakenly attacks the digestive tract, leading to inflammation and tissue damage.

Key points about ulcerative colitis:

What are the symptoms of ulcerative colitis?

The symptoms of ulcerative colitis can vary in severity and may include:

  • Diarrhea, often with blood or pus
  • Abdominal pain and cramping
  • Rectal bleeding
  • Urgent need to have a bowel movement
  • Frequent bowel movements, often accompanied by a feeling of incomplete emptying
  • Weight loss
  • Fatigue
  • Loss of appetite
  • Fever (in severe cases)

Types: Ulcerative colitis can be classified based on the location and extent of inflammation in the colon and rectum:

  • Ulcerative proctitis: Inflammation limited to the rectum.
  • Proctosigmoiditis: Inflammation involving the rectum and the sigmoid colon (lower part of the colon).
  • Left-sided colitis: Inflammation extending from the rectum up to the splenic flexure (the bend near the spleen).
  • Pancolitis: Inflammation involving the entire colon, from the rectum to the cecum (the beginning of the colon).

Causes: The exact cause of ulcerative colitis is unknown, but it is believed to involve a combination of genetic, environmental, and immune system factors. Genetic predisposition, dysregulation of the immune system, and environmental triggers (such as diet, stress, or infections) may all play a role in the development of the condition.

Diagnosis: Ulcerative colitis is diagnosed based on a combination of medical history, physical examination, laboratory tests, imaging studies (such as colonoscopy or sigmoidoscopy), and biopsy of the colon and rectum. Differential diagnosis may be necessary to distinguish UC from other gastrointestinal conditions, such as Crohn’s disease or infectious colitis.

Study Details

Volunteers may qualify:

  • >=18 to 75 Years Old
  • Diagnosed with Ulcerative Colitis
  • Sex: Any
  • Ethnicity: Any

Volunteers Receive:

  • Study-related exams. ( No Cost)
  • Available Transportation
  • Compensation for time and travel
  • No insurance is necessary.
  • Specialist Consultation
  • Medication Available ( No Cost)
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